Current knowledge of COVID-19: Advances, challenges and future perspectives

The pandemic of coronavirus disease 2019 (COVID-19) has already evoked massive influence. The global pandemic has been ravaging the whole world for a year, with the number of confirmed human infection cases over 150 million and a death toll exceeding 3 million. Although the genomic sequence of the c...

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Main Authors:	Yuhan Wu, Zhuobing Peng, Yongxue Yan, Jintao Hu, Yalong Wang, Xiaoyu Wang, Ruchao Peng, Daniel Watterson, Yi Shi
Format:	Article
Language:	English
Published:	Elsevier 2021-08-01
Series:	Biosafety and Health
Subjects:	COVID-19 SARS-CoV-2 Virus origin Transmission Virus infection
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590053621000616

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spelling	doaj-ef4139f65b1440c880ea9e631ba9f6962021-09-03T04:46:50ZengElsevierBiosafety and Health2590-05362021-08-0134202209Current knowledge of COVID-19: Advances, challenges and future perspectivesYuhan Wu0Zhuobing Peng1Yongxue Yan2Jintao Hu3Yalong Wang4Xiaoyu Wang5Ruchao Peng6Daniel Watterson7Yi Shi8College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; MGI, BGI-Shenzhen, Shenzhen 518083, ChinaCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, ChinaHuitong Experimental Station of Forest Ecology, CAS Key Laboratory of Forest Ecology and Management, Institute of Applied Ecology, Shenyang 110164, ChinaMelbourne School of Engineering, the University of Melbourne, Parkville, VIC 3010, AustraliaThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Science, School of Life Science, Tsinghua University, Beijing 100084, ChinaMOE Laboratory of Biosystem Homeostasis and Protection, College of Life Sciences, Zhejiang University, Hangzhou 310058, ChinaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, ChinaAustralian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, AustraliaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Corresponding author: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.The pandemic of coronavirus disease 2019 (COVID-19) has already evoked massive influence. The global pandemic has been ravaging the whole world for a year, with the number of confirmed human infection cases over 150 million and a death toll exceeding 3 million. Although the genomic sequence of the cognate pathogen SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has been quickly determined, there are still many unknown aspects, including the virus origin and evolution trend, and the effectiveness of current vaccines and drugs against the mutating virus. This review summarizes current knowledge and advances about COVID-19, including virus origin, transmission and infection, with the aim to improve the understanding of COVID-19 and provide a new perspective for future studies.http://www.sciencedirect.com/science/article/pii/S2590053621000616COVID-19SARS-CoV-2Virus originTransmissionVirus infection
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yuhan Wu Zhuobing Peng Yongxue Yan Jintao Hu Yalong Wang Xiaoyu Wang Ruchao Peng Daniel Watterson Yi Shi
spellingShingle	Yuhan Wu Zhuobing Peng Yongxue Yan Jintao Hu Yalong Wang Xiaoyu Wang Ruchao Peng Daniel Watterson Yi Shi Current knowledge of COVID-19: Advances, challenges and future perspectives Biosafety and Health COVID-19 SARS-CoV-2 Virus origin Transmission Virus infection
author_facet	Yuhan Wu Zhuobing Peng Yongxue Yan Jintao Hu Yalong Wang Xiaoyu Wang Ruchao Peng Daniel Watterson Yi Shi
author_sort	Yuhan Wu
title	Current knowledge of COVID-19: Advances, challenges and future perspectives
title_short	Current knowledge of COVID-19: Advances, challenges and future perspectives
title_full	Current knowledge of COVID-19: Advances, challenges and future perspectives
title_fullStr	Current knowledge of COVID-19: Advances, challenges and future perspectives
title_full_unstemmed	Current knowledge of COVID-19: Advances, challenges and future perspectives
title_sort	current knowledge of covid-19: advances, challenges and future perspectives
publisher	Elsevier
series	Biosafety and Health
issn	2590-0536
publishDate	2021-08-01
description	The pandemic of coronavirus disease 2019 (COVID-19) has already evoked massive influence. The global pandemic has been ravaging the whole world for a year, with the number of confirmed human infection cases over 150 million and a death toll exceeding 3 million. Although the genomic sequence of the cognate pathogen SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has been quickly determined, there are still many unknown aspects, including the virus origin and evolution trend, and the effectiveness of current vaccines and drugs against the mutating virus. This review summarizes current knowledge and advances about COVID-19, including virus origin, transmission and infection, with the aim to improve the understanding of COVID-19 and provide a new perspective for future studies.
topic	COVID-19 SARS-CoV-2 Virus origin Transmission Virus infection
url	http://www.sciencedirect.com/science/article/pii/S2590053621000616
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Current knowledge of COVID-19: Advances, challenges and future perspectives

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