Pharmacokinetic evaluation of two pirfenidone formulations in patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

Pharmacokinetic evaluation of two pirfenidone formulations in patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by an abnormal activation of lung epithelium and fibroblasts, as well as an excessive accumulation of extracellular matrix. Pirfenidone was introduced as a therapeutic option for IPF and chronic hypersensitive pneum...

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Bibliographic Details
Main Authors: Lina Marcela Barranco-Garduño, Ivette Buendía-Roldan, Juan Jose Rodriguez, Rodrigo González-Ramírez, Ariadna N. Cervantes-Nevárez, Juan Carlos Neri-Salvador, Miriam del Carmen Carrasco-Portugal, Gilberto Castañeda-Hernández, Karen Martinez-Espinosa, Moisés Selman, Francisco Javier Flores-Murrieta
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Heliyon
Subjects:
Pharmaceutical science
Biological Sciences
Health Sciences
Respiratory System
Pharmacology
Internal Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020321228

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