Improvement in the Anti-Tumor Efficacy of Doxorubicin Nanosponges in In Vitro and in Mice Bearing Breast Tumor Models

Improvement in the Anti-Tumor Efficacy of Doxorubicin Nanosponges in In Vitro and in Mice Bearing Breast Tumor Models

Doxorubicin (DOX) is an anthracycline widely used in cancer therapy and in particular in breast cancer treatment. The treatment with DOX appears successful, but it is limited by a severe cardiotoxicity. This work evaluated the in vitro and in vivo anticancer effect of a new formulation of β...

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Bibliographic Details
Main Authors: Monica Argenziano, Casimiro Luca Gigliotti, Nausicaa Clemente, Elena Boggio, Benedetta Ferrara, Francesco Trotta, Stefania Pizzimenti, Giuseppina Barrera, Renzo Boldorini, Federica Bessone, Umberto Dianzani, Roberta Cavalli, Chiara Dianzani
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
β-cyclodextrin nanosponges
doxorubicin
breast cancer
balb-neut mice
epr effect
Online Access:https://www.mdpi.com/2072-6694/12/1/162

Internet

https://www.mdpi.com/2072-6694/12/1/162

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