Different Therapeutic Interventions And Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management

Sickle cell disease is a genetic disorder caused by sickle haemoglobin. In many forms of the disease, the red blood cells can change shape upon deoxygenation due to abnormal sickle haemoglobin polymerisation. The haemoglobin proteins stick to each other, causing the cell to have a rigid surface and...

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Bibliographic Details
Main Authors: Ngozi Awa Imaga, Oluwole Taiwo
Format: Article
Language:English
Published: European Medical Journal 2017-08-01
Series:European Medical Journal Hematology
Subjects:
Online Access:https://www.emjreviews.com/hematology/article/different-therapeutic-interventions-and-mechanisms-of-action-of-antisickling-agents-currently-in-use-in-sickle-cell-disease-management/