Different Therapeutic Interventions And Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management
Sickle cell disease is a genetic disorder caused by sickle haemoglobin. In many forms of the disease, the red blood cells can change shape upon deoxygenation due to abnormal sickle haemoglobin polymerisation. The haemoglobin proteins stick to each other, causing the cell to have a rigid surface and...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
European Medical Journal
2017-08-01
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Series: | European Medical Journal Hematology |
Subjects: | |
Online Access: | https://www.emjreviews.com/hematology/article/different-therapeutic-interventions-and-mechanisms-of-action-of-antisickling-agents-currently-in-use-in-sickle-cell-disease-management/ |