Genomic instability in mutant p53 cancer cells upon entotic engulfment
Cell-in-cell (CIC) structures are frequently observed in cancers; however, it is unclear how their formation contributes to tumorigenesis. Here, the authors show that the high frequency of CIC is linked to mutant p53 status and CIC containing p53 mutant cancer cells are pro-tumorigenic due to enhanc...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-05368-1 |