Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes

Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes

<p>Abstract</p> <p>Background</p> <p>Human immunodeficiency virus type 1 (HIV-1)-based gene delivery systems are popular due to their superior efficiency of transduction of primary cells. However, these systems cannot be readily used for delivery of anti-HIV-1 genes tha...

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Bibliographic Details
Main Author:	Srinivasakumar Narasimhachar
Format:	Article
Language:	English
Published:	BMC 2008-06-01
Series:	AIDS Research and Therapy
Online Access:	http://www.aidsrestherapy.com/content/5/1/11

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