IL-4 Receptor-Alpha Signalling of Intestinal Epithelial Cells, Smooth Muscle Cells, and Macrophages Plays a Redundant Role in Oxazolone Colitis

A hallmark of ulcerative colitis is the chronic colonic inflammation, which is the result of a dysregulated intestinal mucosal immune response. Epithelial barrier disruption which allows the entry of microorganisms eventually leads to more aggressive inflammation and potentially the removal of the c...

Full description

Bibliographic Details
Main Authors: Jennifer Claire Hoving, Roanne Keeton, Maxine A. Höft, Mumin Ozturk, Patricia Otieno-Odhiambo, Frank Brombacher
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/4361043