Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.

Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.

The Sleeping Beauty (SB) transposon is a non-viral integrating vector system with proven efficacy for gene transfer and functional genomics. However, integration efficiency is negatively affected by the length of the transposon. To optimize the SB transposon machinery, the inverted repeats and the t...

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Bibliographic Details
Main Authors:	Giandomenico Turchiano, Maria Carmela Latella, Andreas Gogol-Döring, Claudia Cattoglio, Fulvio Mavilio, Zsuzsanna Izsvák, Zoltán Ivics, Alessandra Recchia
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0112712

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