Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality

The initial heart is composed of a myocardial tube lined by endocardial cells. The TGFβ superfamily is known to play an important role, as BMPs from the myocardium signal to the overlying endocardium to create an environment for EMT. Subsequently, BMP and TGFβ signaling pathways synergize to form pr...

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Bibliographic Details
Main Authors: Paige Snider, Olga Simmons, Jian Wang, Chinh Q. Hoang, Simon J. Conway
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/1/3/214