Genetic Characterization of Fusion Protein of Human Respiratory Syncytial Virus: Beijing

• Main Authors: Lu Qi, Zhao Chun-xia, Shen Kun-ling, Xu Wen-bo, Zhang Yan, Yu Jia-lin, Yang Xi-qiang
• Format: Article
• Language: English
• Published: Sciendo 2012-06-01
• Series: Infection International
• Subjects: Human respiratory syncytial virus; F protein; Nucleotide sequence; Amino acid sequence
• Online Access: http://www.degruyter.com/view/j/ii.2012.1.issue-2/ii-2017-0011/ii-2017-0011.xml?format=INT

Objective Fusion protein is a subunit of the human respiratory syncytial virus (HRSV) and a potential vaccine candidate. Thus, a study on the genetic characteristics of F protein was considered important for further investigations in this field. The aim of this study was to determine the prevalence and genetic diversity of the F gene of HRSV infections in hospitalized pediatric patients in Beijing with acute lower respiratory tract infections and to compare the circulating genotypes that are currently found worldwide.