Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation

Aims and Hypothesis: This study aims to investigate the mechanism involved in intracellular regulation of EGFR degradation induced by EGF.Methods: Phosphorylation of proteins related to EGFR signaling was examined by western blot analysis. Activation, connection between Rab35 and folliculin (FLCN) w...

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Bibliographic Details
Main Authors: Jianchao Zheng, Biao Duan, Shixiu Sun, Jie Cui, Jun Du, Yujie Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
EGFR
degradation
FLCN
Rab35
feedback
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00688/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00688/full

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