Nutlin3a Contributes to the Cytoplasmic Retention of Androgen Receptor
Prostate cancer cells need androgens to grow and maintain like normal prostate cells, both utilize that Androgen Receptor (AR) function. Androgen receptor (AR) is expressed throughout the prostate cancer progression plays a critical role as a transcription factor in castration-dependent stages of di...
Main Authors: | Gulseren Ozduman, Bilge Debelec Butuner, Kemal Sami Korkmaz |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
|
Series: | Proceedings |
Subjects: | |
Online Access: | https://www.mdpi.com/2504-3900/2/25/1580 |
Similar Items
-
The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276
by: Ruidong Li, et al.
Published: (2020-08-01) -
Dynamic behavior of the p53-Mdm2 core module under the action of drug Nutlin and dual delays
by: Juenu Yang, et al.
Published: (2021-05-01) -
Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways
by: Kengo Shimazu, et al.
Published: (2017-05-01) -
MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?
by: Samy A. Azer
Published: (2018-03-01) -
Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells
by: Veronica Tisato, et al.
Published: (2014-01-01)