Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

The structure of human tumor suppressor p53 in complex with the antiapoptotic protein BCL-xL reveals the basis of the p53–BCL-xL interaction and provides insight into the mechanisms of p53-mediated mitochondrial apoptosis.

Bibliographic Details
Main Authors: Hudie Wei, Lingzhi Qu, Shuyan Dai, Yun Li, Haolan Wang, Yilu Feng, Xiaojuan Chen, Longying Jiang, Ming Guo, Jun Li, Zhuchu Chen, Lin Chen, Ye Zhang, Yongheng Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22655-6

Internet

https://doi.org/10.1038/s41467-021-22655-6

Similar Items