Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca<sup>2+</sup> Channels and Activation of CB<sub>1</sub> Receptors

Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca<sup>2+</sup> Channels and Activation of CB<sub>1</sub> Receptors

The aim of this work was to determine whether Capsaicin may exert a vascular regulation through the activation of CB<sub>1</sub> and/or CB<sub>2</sub> receptors causing vasorelaxation in the rat aorta. Our results show the location of TRPV1 mainly in the endothelial and smoot...

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Main Authors: Felipa Andrade, Cinthia Rangel-Sandoval, Alejandrina Rodríguez-Hernández, Evelyn López-Dyck, Alejandro Elizalde, Adolfo Virgen-Ortiz, Edgar Bonales-Alatorre, Georgina Valencia-Cruz, Enrique Sánchez-Pastor
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
cannabinoid receptor 1
TRPV1
Capsaicin
vasorelaxation
Online Access:https://www.mdpi.com/1420-3049/25/17/3957

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