The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells

Multidrug resistance (MDR) is often attributed to the over-expression of P-glycoprotein (P-gp), which prevents the accumulation of anticancer drugs within cells by virtue of its active drug efflux capacity. We have previously described the intercellular transfer of P-gp via extracellular vesicles (E...

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Bibliographic Details
Main Authors: Deep Pokharel, Matthew P. Padula, Jamie F. Lu, Ritu Jaiswal, Steven P. Djordjevic, Mary Bebawy
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/3/290