Treatment modalities of necrobiosis lipoidica: a concise systematic review

Necrobiosis lipoidica (NL) is a rare inflammatory granulomatous skin disorder closely associated with diabetes mellitus. The aim of this paper is to review and discuss all the treatment modalities proposed and tested for this disease. A systematic review of the existing literature was conducted to i...

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Main Authors: Amir Feily, Shadi Mehraban
Format: Article
Language:English
Published: PAGEPress Publications 2015-06-01
Series:Dermatology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/dr/article/view/5749
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spelling doaj-eeca990286d44331b0bef179b01a31712020-11-25T03:47:55ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062015-06-017210.4081/dr.2015.57493086Treatment modalities of necrobiosis lipoidica: a concise systematic reviewAmir Feily0Shadi Mehraban1Department of Dermatology, Jahrom University of Medical SciencesDepartment of Dermatology, Jahrom University of Medical SciencesNecrobiosis lipoidica (NL) is a rare inflammatory granulomatous skin disorder closely associated with diabetes mellitus. The aim of this paper is to review and discuss all the treatment modalities proposed and tested for this disease. A systematic review of the existing literature was conducted to investigate all the available data and summarize all the clinical trials, case reports and original articles on NL. Two major databases (PubMed and Google Scholar) were used. We have examined about 70 articles. Numerous treatment modalities have been currently investigated to compare recalcitrant NL. Being rare, most of the studies regarding this disease are case reports or small-scale clinical trials. We have found that, in spite of plentiful investigations carried out during the years, there is no treatment modality that has proved to be utterly satisfactory in treating NL.http://www.pagepress.org/journals/index.php/dr/article/view/5749Necrobisis lipoidicatreatmentreview
collection DOAJ
language English
format Article
sources DOAJ
author Amir Feily
Shadi Mehraban
spellingShingle Amir Feily
Shadi Mehraban
Treatment modalities of necrobiosis lipoidica: a concise systematic review
Dermatology Reports
Necrobisis lipoidica
treatment
review
author_facet Amir Feily
Shadi Mehraban
author_sort Amir Feily
title Treatment modalities of necrobiosis lipoidica: a concise systematic review
title_short Treatment modalities of necrobiosis lipoidica: a concise systematic review
title_full Treatment modalities of necrobiosis lipoidica: a concise systematic review
title_fullStr Treatment modalities of necrobiosis lipoidica: a concise systematic review
title_full_unstemmed Treatment modalities of necrobiosis lipoidica: a concise systematic review
title_sort treatment modalities of necrobiosis lipoidica: a concise systematic review
publisher PAGEPress Publications
series Dermatology Reports
issn 2036-7392
2036-7406
publishDate 2015-06-01
description Necrobiosis lipoidica (NL) is a rare inflammatory granulomatous skin disorder closely associated with diabetes mellitus. The aim of this paper is to review and discuss all the treatment modalities proposed and tested for this disease. A systematic review of the existing literature was conducted to investigate all the available data and summarize all the clinical trials, case reports and original articles on NL. Two major databases (PubMed and Google Scholar) were used. We have examined about 70 articles. Numerous treatment modalities have been currently investigated to compare recalcitrant NL. Being rare, most of the studies regarding this disease are case reports or small-scale clinical trials. We have found that, in spite of plentiful investigations carried out during the years, there is no treatment modality that has proved to be utterly satisfactory in treating NL.
topic Necrobisis lipoidica
treatment
review
url http://www.pagepress.org/journals/index.php/dr/article/view/5749
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