Construction of Salmonella Pullorum ghost by co-expression of lysis gene E and the antimicrobial peptide SMAP29 and evaluation of its immune efficacy in specific-pathogen-free chicks

In this study, a safety enhanced Salmonella Pullorum (S. Pullorum) ghost was constructed using an antimicrobial peptide gene, and evaluated for its potential as a Pullorum disease (PD) vaccine candidate. The antimicrobial peptide SMAP29 was co-expressed with lysis gene E to generate S. Pullorum ghos...

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Bibliographic Details
Main Authors: Qiu-feng TIAN, Wei ZHOU, Wei SI, Fei YI, Xin HUA, Min YUE, Li-ping CHEN, Si-guo LIU, Shen-ye YU
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Integrative Agriculture
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311917616964