Preclinical evaluation of the immunogenicity and safety of an inactivated enterovirus 71 candidate vaccine.

Human enterovirus 71 (EV71) is a significant cause of morbidity and mortality from Hand, Foot and Mouth Disease (HFMD) and neurological complications, particularly in young children in the Asia-Pacific region. There are no vaccines or antiviral therapies currently available for prevention or treatme...

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Bibliographic Details
Main Authors: Shi-Hsia Hwa, Yock Ann Lee, Joseph N Brewoo, Charalambos D Partidos, Jorge E Osorio, Joseph D Santangelo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3820736?pdf=render