A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
Adamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. Ther...
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Series: | BioMed Research International |
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doaj-eeac0b8e8e1c4eefaea8db847d05ec462020-11-24T20:42:05ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/120519120519A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s DiseaseMichele Figus0Chiara Posarelli1Timothy G. Albert2Rosaria Talarico3Marco Nardi4Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyAdamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet’s disease.http://dx.doi.org/10.1155/2015/120519 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Michele Figus Chiara Posarelli Timothy G. Albert Rosaria Talarico Marco Nardi |
spellingShingle |
Michele Figus Chiara Posarelli Timothy G. Albert Rosaria Talarico Marco Nardi A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease BioMed Research International |
author_facet |
Michele Figus Chiara Posarelli Timothy G. Albert Rosaria Talarico Marco Nardi |
author_sort |
Michele Figus |
title |
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease |
title_short |
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease |
title_full |
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease |
title_fullStr |
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease |
title_full_unstemmed |
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease |
title_sort |
clinical picture of the visual outcome in adamantiades-behçet’s disease |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2015-01-01 |
description |
Adamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet’s disease. |
url |
http://dx.doi.org/10.1155/2015/120519 |
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