A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease

Adamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. Ther...

Full description

Bibliographic Details
Main Authors: Michele Figus, Chiara Posarelli, Timothy G. Albert, Rosaria Talarico, Marco Nardi
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/120519
id doaj-eeac0b8e8e1c4eefaea8db847d05ec46
record_format Article
spelling doaj-eeac0b8e8e1c4eefaea8db847d05ec462020-11-24T20:42:05ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/120519120519A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s DiseaseMichele Figus0Chiara Posarelli1Timothy G. Albert2Rosaria Talarico3Marco Nardi4Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, ItalyAdamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet’s disease.http://dx.doi.org/10.1155/2015/120519
collection DOAJ
language English
format Article
sources DOAJ
author Michele Figus
Chiara Posarelli
Timothy G. Albert
Rosaria Talarico
Marco Nardi
spellingShingle Michele Figus
Chiara Posarelli
Timothy G. Albert
Rosaria Talarico
Marco Nardi
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
BioMed Research International
author_facet Michele Figus
Chiara Posarelli
Timothy G. Albert
Rosaria Talarico
Marco Nardi
author_sort Michele Figus
title A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
title_short A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
title_full A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
title_fullStr A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
title_full_unstemmed A Clinical Picture of the Visual Outcome in Adamantiades-Behçet’s Disease
title_sort clinical picture of the visual outcome in adamantiades-behçet’s disease
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Adamantiades-Behçet’s disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet’s disease.
url http://dx.doi.org/10.1155/2015/120519
work_keys_str_mv AT michelefigus aclinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT chiaraposarelli aclinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT timothygalbert aclinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT rosariatalarico aclinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT marconardi aclinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT michelefigus clinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT chiaraposarelli clinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT timothygalbert clinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT rosariatalarico clinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
AT marconardi clinicalpictureofthevisualoutcomeinadamantiadesbehcetsdisease
_version_ 1716823263412224000