2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine

2′-Chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine

The compound 2′-chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine was obtained with a good yield by the reaction of 2-chloro-4-(1-methyl-1H-imidazol-2-yl)pyridine with (2-chloropyridin-4-yl)boronic acid and structurally characterized by nuclear magnetic resonance (1H-NMR and 13C-NMR), thin-layer...

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Bibliographic Details
Main Authors: Dhafer Saber Zinad, Dunya L. AL-Duhaidahaw, Ahmed Al-Amiery
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molbank
Subjects:
Suzuki–Miyaura
imidazole
boronic acid
palladium-catalyzed
mass spectrometry
Online Access:http://www.mdpi.com/1422-8599/2019/1/M1040
Description
Summary:The compound 2′-chloro-4-(1-methyl-1H-imidazol-2-yl)-2,4′-bipyridine was obtained with a good yield by the reaction of 2-chloro-4-(1-methyl-1H-imidazol-2-yl)pyridine with (2-chloropyridin-4-yl)boronic acid and structurally characterized by nuclear magnetic resonance (1H-NMR and 13C-NMR), thin-layer chromatography–mass spectrometry (TLC–MS), HPLC, gas chromatography–mass spectrometry (GC–MS), and elemental analysis. The functionalization of the pyridine was achieved by the palladium-catalyzed Suzuki–Miyaura carbon–carbon cross-coupling reaction that afforded the target compound.
ISSN:1422-8599

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