Multidimensional phenotyping predicts lifespan and quantifies health in Caenorhabditis elegans.

Ageing affects a wide range of phenotypes at all scales, but an objective measure of ageing remains challenging, even in simple model organisms. To measure the ageing process, we characterized the sequence of alterations of multiple phenotypes at organismal scale. Hundreds of morphological, postural...

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Bibliographic Details
Main Authors: Céline N Martineau, André E X Brown, Patrick Laurent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008002