miR-10a is aberrantly overexpressed in <it>Nucleophosmin1 </it>mutated acute myeloid leukaemia and its suppression induces cell death

miR-10a is aberrantly overexpressed in <it>Nucleophosmin1 </it>mutated acute myeloid leukaemia and its suppression induces cell death

<p>Abstract</p> <p>Background</p> <p>Acute myeloid leukaemia (AML) with nucleophosmin-1 (<it>NPM1</it>) mutation is a major subtype of AML. The <it>NPM1 </it>mutation induces a myeloproliferative disorder, but evidence indicates that other insult...

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Bibliographic Details
Main Authors: Bryant Adam, Palma Catalina A, Jayaswal Vivek, Yang Yee, Lutherborrow Mark, Ma David DF
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Molecular Cancer
Subjects:
Acute myeloid leukaemia (AML)
Nucleophosphmin1
microRNA
miR-10a
microarray
Cell death
Online Access:http://www.molecular-cancer.com/content/11/1/8

Internet

http://www.molecular-cancer.com/content/11/1/8

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