HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.

HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.

Human embryonic stem cells (hESCs) could provide a major window into human developmental biology, because the differentiation methods from hESCs mimic human embryogenesis. We previously reported that the overexpression of hematopoietically expressed homeobox (HHEX) in the hESC-derived definitive end...

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Main Authors: Hitoshi Watanabe, Kazuo Takayama, Mitsuru Inamura, Masashi Tachibana, Natsumi Mimura, Kazufumi Katayama, Katsuhisa Tashiro, Yasuhito Nagamoto, Fuminori Sakurai, Kenji Kawabata, Miho Kusuda Furue, Hiroyuki Mizuguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3961246?pdf=render

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http://europepmc.org/articles/PMC3961246?pdf=render

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