Pseudomonas aeruginosa cytotoxicity is attenuated at high cell density and associated with the accumulation of phenylacetic acid.

Pseudomonas aeruginosa cytotoxicity is attenuated at high cell density and associated with the accumulation of phenylacetic acid.

P. aeruginosa is known to cause acute cytotoxicity against various human and animal cells and tissues.Intriguingly, however, in this study we noticed that while a low cell density inoculum of P. aeruginosa caused severe cytotoxicity against human lung tissue cell line A549, increasing the cell densi...

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Bibliographic Details
Main Authors: Jianhe Wang, Yihu Dong, Tielin Zhou, Xiaoling Liu, Yinyue Deng, Chao Wang, Jasmine Lee, Lian-Hui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612096?pdf=render

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http://europepmc.org/articles/PMC3612096?pdf=render

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