Trypanosoma cruzi cell death induced by the Morita-Baylis-Hillman adduct 3-Hydroxy-2-methylene-3-(4-nitrophenylpropanenitrile).

Trypanosoma cruzi cell death induced by the Morita-Baylis-Hillman adduct 3-Hydroxy-2-methylene-3-(4-nitrophenylpropanenitrile).

Chagas disease, caused by the protozoan Trypanosoma cruzi, remains a serious health concern due to the lack of effective vaccines or satisfactory treatment. In the search for new compounds against this neglected disease, we have previously demonstrated that the compound 3-Hydroxy-2-methylene-3-(4-ni...

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Bibliographic Details
Main Authors: Jana M Sandes, Adriana Fontes, Carlos G Regis-da-Silva, Maria C A Brelaz de Castro, Claudio G Lima-Junior, Fábio P L Silva, Mário L A A Vasconcellos, Regina C B Q Figueiredo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979736?pdf=render

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http://europepmc.org/articles/PMC3979736?pdf=render

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