Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.

<h4>Background</h4>While a number of autosomal dominant and autosomal recessive cancer syndromes have an associated spectrum of cancers, the prevalence and variety of cancer predisposition mutations in patients with multiple primary cancers have not been extensively investigated. An unde...

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Bibliographic Details
Main Authors: Antonia L Pritchard, Peter A Johansson, Vaishnavi Nathan, Madeleine Howlie, Judith Symmons, Jane M Palmer, Nicholas K Hayward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0194098