Novel approach to meta-analysis of microarray datasets reveals muscle remodeling-related drug targets and biomarkers in Duchenne muscular dystrophy.
Elucidation of new biomarkers and potential drug targets from high-throughput profiling data is a challenging task due to a limited number of available biological samples and questionable reproducibility of differential changes in cross-dataset comparisons. In this paper we propose a novel computati...
Main Authors: | Ekaterina Kotelnikova, Maria A Shkrob, Mikhail A Pyatnitskiy, Alessandra Ferlini, Nikolai Daraselia |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3271016?pdf=render |
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