Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

Anti-CD20 therapy is effective in idiopathic nephrotic syndrome (INS). However, transient or sustained hypogammaglobulinemia predisposing to an increased risk of infectious diseases can follow treatment in some patients. We analyzed the long-term effects of anti-CD20 therapy on immunological memory...

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Bibliographic Details
Main Authors: Manuela Colucci, Rita Carsetti, Jessica Serafinelli, Salvatore Rocca, Laura Massella, Antonio Gargiulo, Anna Lo Russo, Claudia Capponi, Nicola Cotugno, Ottavia Porzio, Andrea Onetti Muda, Paolo Palma, Francesco Emma, Marina Vivarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
immunologic memory
hypogammaglobulinaemia
B cells
clinical immunology
pediatric nephrology
idiopathic nephrotic syndrome (INS)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01653/full

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