Synthesis of Camalexin

In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis...

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Main Authors: V. Kovacik, M. Ruzinsky, J. Zaletova, P. Kutschy, M. Dzurilla
Format: Article
Language:English
Published: MDPI AG 2001-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/6/9/716/
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spelling doaj-ee6f361518d64b809f201d31a046525b2020-11-25T01:47:46ZengMDPI AGMolecules1420-30492001-08-016971672010.3390/60900716Synthesis of CamalexinV. KovacikM. RuzinskyJ. ZaletovaP. KutschyM. DzurillaIn this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, 1H NMR, 13C NMR and mass spectroscopy.http://www.mdpi.com/1420-3049/6/9/716/Camalexinphytoalexinsindoles
collection DOAJ
language English
format Article
sources DOAJ
author V. Kovacik
M. Ruzinsky
J. Zaletova
P. Kutschy
M. Dzurilla
spellingShingle V. Kovacik
M. Ruzinsky
J. Zaletova
P. Kutschy
M. Dzurilla
Synthesis of Camalexin
Molecules
Camalexin
phytoalexins
indoles
author_facet V. Kovacik
M. Ruzinsky
J. Zaletova
P. Kutschy
M. Dzurilla
author_sort V. Kovacik
title Synthesis of Camalexin
title_short Synthesis of Camalexin
title_full Synthesis of Camalexin
title_fullStr Synthesis of Camalexin
title_full_unstemmed Synthesis of Camalexin
title_sort synthesis of camalexin
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2001-08-01
description In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, 1H NMR, 13C NMR and mass spectroscopy.
topic Camalexin
phytoalexins
indoles
url http://www.mdpi.com/1420-3049/6/9/716/
work_keys_str_mv AT vkovacik synthesisofcamalexin
AT mruzinsky synthesisofcamalexin
AT jzaletova synthesisofcamalexin
AT pkutschy synthesisofcamalexin
AT mdzurilla synthesisofcamalexin
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