“Real-Time” High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report

“Real-Time” High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report

Antibiotic management of infections with multidrug-resistant organisms (MDRO) represents a complex clinical challenge. We report here the first patient with a severe MDRO infection managed with assistance of a novel “real-time” 3-day high-throughput screen (HTS) that allowed screening of 9 drugs in...

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Bibliographic Details
Main Authors: Wei Sun, Shayla Hesse, Miao Xu, Richard W. Childs, Wei Zheng, Peter R. Williamson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Medicine
Subjects:
multidrug-resistant organisms
Klebsiella pneumoniae
real-time drug test
antibiotic combination therapy
drug repurposing screen
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00267/full

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