The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition

The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition

Backgroundβ-cell death due to endoplasmic reticulum (ER) stress has been regarded as an important pathogenic component of type 2 diabetes. The possibility has been suggested that sulfonylurea, currently being used as one of the main oral hypoglycemic agents of type 2 diabetes, increases ER stress, w...

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Bibliographic Details
Main Authors: Min Jeong Kwon, Hye Suk Chung, Chang Shin Yoon, Jung Hae Ko, Hae Jung Jun, Tae Kyun Kim, Soon Hee Lee, Kyung Soo Ko, Byoung Doo Rhee, Mi Kyung Kim, Jeong Hyun Park
Format: Article
Language:English
Published: Korean Diabetes Association 2011-10-01
Series:Diabetes & Metabolism Journal
Subjects:
Apoptosis
Endoplasmic reticulum stress
Glyburide
Insulin-secreting cells
Online Access:http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-480.pdf

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