Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo

Abstract Background Bladder cancer is a frequently diagnosed urinary system tumor, whose mortality remains rising. Minichromosome maintenance eight homologous recombination repair factor (MCM8), a newly discovered MCM family member, has been shown to be required for DNA replication. Unfortunately, l...

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Bibliographic Details
Main Authors: Wei Zhu, Fei Gao, Hongyi Zhou, Ke Jin, Jianfeng Shao, Zhuoqun Xu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-01948-2