THE VALUE OF THE INTIMA-MEDIA THICKNESS AS A RISK FACTOR FOR CEREBROVASCULAR DISEASE IN FIRST DEGREE RELATIVES OF DIABETIC TYPE 2 PATIENTS

• Main Authors: C. Filos, G. Mazilu, C.D. Popescu
• Format: Article
• Language: English
• Published: Amaltea Medical Publishing House 2011-09-01
• Series: Romanian Journal of Neurology
• Subjects: intima media thickness; fi rst degree relatives; cerebrovascular disease; diabetes mellitus type 2
• Online Access: https://revistemedicale.amaltea.ro/Romanian_Journal_of_NEUROLOGY/Revista_Romana_de_NEUROLOGIE-2011-Nr.3/RJN_2011_3_Art-06.pdf

Cerebrovascular diseases and diabetes mellitus have become in the last years the first cause of mortality and major invalidity throughout the world. Intima media thickness is a very good marker for subclinical atherosclerosis and also for predicting future cardio and cerebrovascular events. The aim of this study is to try to find out the value of the intima media thickness as a risk factor for cerebrovascular disease in first degree relatives of diabetic type 2 patients. Material and method: we evaluated two groups, selected by well defined criteria, divided into the witness group of 21 subjects and the study group of 41 subjects. The intima media thickness was measured with a standard method, by cervical ultrasound mode B, at the common carotid artery distal wall, both sides left and right. Other parameters measured were weight, height, and body mass index, arterial systolic and diastolic blood pressure. Results: Gender distribution of subjects in the study group was predominantly male (53,6%); regarding the BMI, we could notice that 57% of the study group was overweight, but with normal blood pressure. The IMT value in the study group has varied between 0,6mm and 1,3 mm with an average of 0,82mm on the right side and between 0,5mm and 1,2mm with an average of 0,87mm on the left side. Applying the t-Student test to these values we could see no statistical significance between the two groups analyzed (p>0,05). Conclusion: in this study intima media thickness had no statistical significant value as a risk factor for cerebrovascular disease in first degree relatives of diabetic type 2 patients.