Optimization of multiplex quantitative polymerase chain reaction based on response surface methodology and an artificial neural network-genetic algorithm approach.

Optimization of multiplex quantitative polymerase chain reaction based on response surface methodology and an artificial neural network-genetic algorithm approach.

Multiplex quantitative polymerase chain reaction (qPCR) has found an increasing range of applications. The construction of a reliable and dynamic mathematical model for multiplex qPCR that analyzes the effects of interactions between variables is therefore especially important. This work aimed to an...

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Bibliographic Details
Main Authors: Ping Pan, Weifeng Jin, Xiaohong Li, Yi Chen, Jiahui Jiang, Haitong Wan, Daojun Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6059488?pdf=render

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http://europepmc.org/articles/PMC6059488?pdf=render

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