BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC

<p>Abstract</p> <p>Background</p> <p>We have previously combined statistical alignment and phylogenetic footprinting to detect conserved functional elements without assuming a fixed alignment. Considering a probability-weighted distribution of alignments removes sensiti...

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Bibliographic Details
Main Authors: Miklós István, Novák Ádám, Satija Rahul, Lyngsø Rune, Hein Jotun
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/217