Gold Nanoparticles Inhibit VEGF165-Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway

Gold Nanoparticles Inhibit VEGF165-Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway

The early stages of angiogenesis can be divided into three steps: endothelial cell proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is considered the most important proangiogenic factor; in particular, VEGF165 plays a critical role in angiogenesis. Here, we eva...

Full description

Bibliographic Details
Main Authors:	Yunlong Pan, Qing Wu, Li Qin, Jiye Cai, Bin Du
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2014/418624

Similar Items

The Inhibitory Effects of Gold Nanoparticles on VEGF-A-Induced Cell Migration in Choroid-Retina Endothelial Cells
by: Chi-Ming Chan, et al.
Published: (2019-12-01)

Expression of VEGF<sub>165</sub> and VEGF<sub>165b</sub> in human retinal pigment epithelial cells in hypoxia and high glucose environment
by: Ya-Jing Niu, et al.
Published: (2018-02-01)

Angiogenic Effects of Collagen/Mesoporous Nanoparticle Composite Scaffold Delivering VEGF165
by: Joong-Hyun Kim, et al.
Published: (2016-01-01)

Diabetic neuropathy : a mechanism of TRPV1 sensitisation and the treatment with Vascular Endothelial Growth Factor-A165b (VEGF-A165b)
by: Bestall, Samuel
Published: (2017)

Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury
by: Tian S, et al.
Published: (2015-09-01)

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition
by: Sezin Aday, et al.
Published: (2017-09-01)

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition
by: Zoldan, Janet, et al.
Published: (2018)

The role of VEGF165B in pituitary adenomas pathogenesis
by: Eugen Melnic
Published: (2017-06-01)

Development and Characterization of VEGF165-Chitosan Nanoparticles for the Treatment of Radiation-Induced Skin Injury in Rats
by: Daojiang Yu, et al.
Published: (2016-10-01)

VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas
by: Ana Silvia Corlan, et al.
Published: (2019-03-01)

Expression of Total Vascular Endothelial Growth Factor and the Anti-angiogenic VEGF 165 b Isoform in the Vitreous of Patients with Retinopathy of Prematurity
by: Min Zhao, et al.
Published: (2015-01-01)

Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli.
by: Arefeh Seyedarabi, et al.
Published: (2013-01-01)

VEGF<sub>121</sub>b and VEGF<sub>165</sub>b are weakly angiogenic isoforms of VEGF-A
by: Pio Ruben, et al.
Published: (2010-12-01)

Gene therapy with VEGF 165 for angiogenesis in experimental acute myocardial infarction Terapia gênica com VEGF 165 para angiogênese no infarto agudo do miocárdio experimental
by: Roberto T. Sant'Anna, et al.
Published: (2003-06-01)

Probing high affinity sequences of DNA aptamer against VEGF165.
by: Harleen Kaur, et al.
Published: (2012-01-01)

Neovascularização retiniana induzida por injeções intravítreas de Vegf 165
by: Arana, Luis Augusto
Published: (2012)

Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165
by: Heidrun L. Deissler, et al.
Published: (2017-07-01)

Aspalatone Prevents VEGF-Induced Lipid Peroxidation, Migration, Tube Formation, and Dysfunction of Human Aortic Endothelial Cells
by: Himangshu Sonowal, et al.
Published: (2017-01-01)

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells
by: Stefania Zimbone, et al.
Published: (2020-04-01)

Intraocular Penetration of a vNAR: In Vivo and In Vitro VEGF165 Neutralization
by: Tanya A. Camacho-Villegas, et al.
Published: (2018-03-01)

Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF165 and Thrombin
by: Anna Meneghello, et al.
Published: (2013-10-01)

Delivery of IFNa and VEGF165b by microencapsulated cells: preparation and «in vitro» analysis
by: Afkhami Zarreh, Fatemeh
Published: (2009)

The Mechanisms of Lung Carcinogenesis in Human VEGF-A165 Overexpressed Transgenic Mice.
by: Yu-Ching Chou, et al.

Carbon ion radiation inhibits glioma and endothelial cell migration induced by secreted VEGF.
by: Yang Liu, et al.
Published: (2014-01-01)

Estimation of systemic distribution and angiogenic effect of pl-VEGF165 in the model of limb ischemia
by: М. А. Юдин, et al.
Published: (2016-01-01)

Correction: Carbon Ion Radiation Inhibits Glioma and Endothelial Cell Migration Induced by Secreted VEGF.
by: Yang Liu, et al.
Published: (2015-01-01)

Short and long-term effects of hVEGF-A(165) in Cre-activated transgenic mice.
by: Pia Leppänen, et al.
Published: (2006-01-01)

Effects of Leukocyte Cell-Derived Chemotaxin 2 (LECT2) on VEGF165-Induced Angiogenesis
by: Wan-Ching Chung, et al.
Published: (2008)

The Pulmonary Tumorigenesis Induced by Human VEGF-A165 Overexpression in the Lung Tissue of Transgenic Mice
by: Pin-Wu Huang, et al.
Published: (2006)

Revascularização precoce do brônquio isquêmico mediante terapia gênica com phVEGF 165
by: Saueressig, Mauricio Guidi
Published: (2007)

Revascularização precoce do brônquio isquêmico mediante terapia gênica com phVEGF 165
by: Saueressig, Mauricio Guidi
Published: (2007)

Revascularização precoce do brônquio isquêmico mediante terapia gênica com phVEGF 165
by: Saueressig, Mauricio Guidi
Published: (2007)

Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165
by: Lim, Dong-Kwon, et al.
Published: (2021)

Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165
by: Lim, Dong-Kwon, et al.
Published: (2022)

Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165
by: Bartlomiej Fedorczyk, et al.
Published: (2019-05-01)

Effects of vascular endothelial growth factor 165 on bone tissue engineering.
by: Lin Feng, et al.
Published: (2013-01-01)

Investigation of Antiangiogenic Tumor Therapy Potential of Microencapsulated HEK293 VEGF165b Producing Cells
by: Fatemeh Afkhami, et al.
Published: (2010-01-01)

Hypothermia reduces VEGF-165 expression, but not osteogenic differentiation of human adipose stem cells under hypoxia.
by: Nick C Leegwater, et al.
Published: (2017-01-01)

Combination Use of BMP2 and VEGF165 Promotes Osseointegration and Stability of Titanium Implants in Irradiated Bone
by: Bo Huang, et al.
Published: (2018-01-01)

TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients
by: Jaenicke Fritz, et al.
Published: (2010-04-01)