Proteomic comparison between different tissue preservation methods for identification of promising biomarkers of urothelial bladder cancer

Abstract Samples in biobanks are generally preserved by formalin-fixation and paraffin-embedding (FFPE) and/or optimal cutting temperature compound (OCT)-embedding and subsequently frozen. Mass spectrometry (MS)-based analysis of these samples is now available via developed protocols, however, the d...

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Bibliographic Details
Main Authors: Alberto Valdés, Athanasios Bitzios, Eszter Kassa, Ganna Shevchenko, Alexander Falk, Per-Uno Malmström, Anca Dragomir, Ulrika Segersten, Sara Bergström Lind
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87003-6