A correlate of HIV-1 control consisting of both innate and adaptive immune parameters best predicts viral load by multivariable analysis in HIV-1 infected viremic controllers and chronically-infected non-controllers.

A correlate of HIV-1 control consisting of both innate and adaptive immune parameters best predicts viral load by multivariable analysis in HIV-1 infected viremic controllers and chronically-infected non-controllers.

HIV-1 infected viremic controllers maintain durable viral suppression below 2000 copies viral RNA/ml without anti-retroviral therapy (ART), and the immunological factor(s) associated with host control in presence of low but detectable viral replication are of considerable interest. Here, we utilized...

Full description

Bibliographic Details
Main Authors:	Costin Tomescu, Qin Liu, Brian N Ross, Xiangfan Yin, Kenneth Lynn, Karam C Mounzer, Jay R Kostman, Luis J Montaner
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25078947/?tool=EBI

Similar Items

Randomized, controlled trial of therapy interruption in chronic HIV-1 infection.
by: Emmanouil Papasavvas, et al.
Published: (2004-12-01)

Sustained Viremic Control in HIV-Infected Patient: Case Report from Nepal
by: Sundar Khadka, et al.
Published: (2018-01-01)

Delineation of Homeostatic Immune Signatures Defining Viremic Non-progression in HIV-1 Infection
by: Amit Kumar Singh, et al.
Published: (2020-03-01)

Differential microRNA expression profile between stimulated PBMCs from HIV-1 infected elite controllers and viremic progressors.
by: Lander Egaña-Gorroño, et al.
Published: (2014-01-01)

Contribution of Innate Responses to Viral Control in HIV-1 Infection
Published: (2020)

Low levels of anti-MPER antibodies are detectable in viremic HIV infected
by: Carrillo J, et al.
Published: (2012-09-01)

Decreased mutation frequencies among immunoglobulin G variable region genes during viremic HIV-1 infection.
by: Elisabeth Bowers, et al.
Published: (2014-01-01)

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
by: Bontems, F., et al.
Published: (2022)

Different immunological phenotypes associated with preserved CD4+ T cell counts in HIV-infected controllers and viremic long term non-progressors.
by: Julie Christine Gaardbo, et al.
Published: (2013-01-01)

Innate Antiviral Response: Role in HIV-1 Infection
by: Paula M. Pitha
Published: (2011-07-01)

Innate immune responses in HIV-1 infected macrophages
by: Tsang, J. M.
Published: (2014)

Control of rebound virus in HIV-1 infection
by: Kusuwan, Siripattra
Published: (2006)

Prevalence of Viremic hepatitis C, hepatitis B, and HIV infection, and vaccination status among prisoners in Stockholm County
by: Caroline Gahrton, et al.
Published: (2019-11-01)

Interferon-α alters host glycosylation machinery during treated HIV infection
by: Leila B. Giron, et al.
Published: (2020-09-01)

FcRL4 Expression Identifies a Pro-inflammatory B Cell Subset in Viremic HIV-Infected Subjects
by: Basile Siewe, et al.
Published: (2017-10-01)

Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients
by: Witwer Kenneth W, et al.
Published: (2012-01-01)

Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV
by: Leila B. Giron, et al.
Published: (2021-06-01)

Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.
by: Nichole R Klatt, et al.
Published: (2014-08-01)

Innate sensing of HIV-infected cells.
by: Alice Lepelley, et al.
Published: (2011-02-01)

Co-expression of multiple inhibitory receptors on CD8+ T cells in viremic and ART-suppressed HIV-1(+) individuals
by: B. Macatangay, et al.
Published: (2015-12-01)

Control of HIV-1 by multiple immunodominant HIV-1-specific CD8+ T cells in HIV-1-infected Japanese individuals
by: Murakoshi H, et al.
Published: (2012-09-01)

Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
by: Hiroyu Hatano, et al.
Published: (2013-01-01)

Adaptive sliding mode control of HIV-1 infection model
by: M.J. Mahmoodabadi, et al.
Published: (2021-01-01)

Viral reservoirs in elite controllers of HIV-1 infection: Implications for HIV cure strategies
by: Bezawit A. Woldemeskel, et al.
Published: (2020-12-01)

Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals.
by: Manuela Fogli, et al.
Published: (2008-07-01)

Innate Lymphoid Cells in HIV/SIV Infections
by: Spandan V. Shah, et al.
Published: (2017-12-01)

Effects of schistosomiasis on susceptibility to HIV-1 infection and HIV-1 viral load at HIV-1 seroconversion: A nested case-control study.
by: Jennifer A Downs, et al.
Published: (2017-09-01)

Role of Dendritic Cells in Natural Immune Control of HIV-1 Infection
by: Enrique Martin-Gayo, et al.
Published: (2019-06-01)

The impact of HLA-Cw*12:02 on control of HIV-1 infection
by: Koyanagi M, et al.
Published: (2012-09-01)

Chemokine control of HIV-1 infection: Beyond a binding competition
by: Wu Yuntao
Published: (2010-10-01)

Fuzzy Modeling and Control of HIV Infection
by: Hassan Zarei, et al.
Published: (2012-01-01)

Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles.
by: Bethsebah Gekonge, et al.
Published: (2012-01-01)

Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection
by: Oya Cingöz, et al.
Published: (2021-02-01)

Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk.
by: Erica Andersen-Nissen, et al.
Published: (2021-03-01)

ZIKV Demonstrates Minimal Pathologic Effects and Mosquito Infectivity in Viremic Cynomolgus Macaques
by: Sasha R. Azar, et al.
Published: (2018-11-01)

P16-06. Control of HIV-1 by HIV-1 Pol-specific CD8+ T cells in chronically HIV-1-infected Japanese cohort
by: Takiguchi M, et al.
Published: (2009-10-01)

The Oral Bacterial Communities of Children with Well-Controlled HIV Infection and without HIV Infection.
by: Brittany E Goldberg, et al.
Published: (2015-01-01)

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.
by: Chiraz Hamimi, et al.
Published: (2016-01-01)

Polymorphims of innate immunity genes influence disease progression in HIV-1 infected children
by: Freguja Riccardo, et al.
Published: (2012-05-01)

Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function.
by: Marta Curriu, et al.
Published: (2012-01-01)