Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature

A woman in her 50s was referred to our department with the chief complaint of nasal congestion and pharyngeal discomfort. The patient had been diagnosed with sleep apnea at the Department of Internal Medicine, and had undergone nasal continuous positive airway pressure (nCPAP) therapy, but her respo...

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Main Authors: Yuma Matsumoto, Hidenori Yokoi, Tetsuya Ikeda, Masachika Fujiwara, Hiroshi Kamma, Naoyuki Kohno
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Clinical Medicine Insights: Case Reports
Online Access:https://doi.org/10.4137/CCRep.S24074
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spelling doaj-ee13ddd813884dec90e49ea1f8d061322020-11-25T01:27:33ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762015-01-01810.4137/CCRep.S24074Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of LiteratureYuma Matsumoto0Hidenori Yokoi1Tetsuya Ikeda2Masachika Fujiwara3Hiroshi Kamma4Naoyuki Kohno5Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan.Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan.Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan.Department of Pathology, Kyorin University School of Medicine, Tokyo, Japan.Department of Pathology, Kyorin University School of Medicine, Tokyo, Japan.Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan.A woman in her 50s was referred to our department with the chief complaint of nasal congestion and pharyngeal discomfort. The patient had been diagnosed with sleep apnea at the Department of Internal Medicine, and had undergone nasal continuous positive airway pressure (nCPAP) therapy, but her response to the treatment was poor. A cystic lesion occupying the nasopharynx, which was detected by nasopharyngeal fiberscopy, computed tomography, and magnetic resonance imaging, was thought to be the cause of the nasal congestion, pharyngeal discomfort, and obstructive sleep apnea syndrome (OSAS). Consequently, the patient underwent extirpation of the lesion under general anesthesia for the purpose of obtaining a definitive diagnosis as well as for treatment of the nasopharyngeal tumor. The diagnosis of intra-adenoid cyst was eventually made based on the pathological findings, which revealed lymphoid tissue accompanied by expansion of the crypt, as well as inflammatory cell infiltration with follicular hyperplasia. After the operation, the patient reported subjective improvement of her symptoms, and began to respond to the nCPAP therapy for her sleep apnea syndrome. Nasopharyngeal cysts, in particular adult intra-adenoid cyst, are relatively rare. The outcomes of the current case indicated that the presence of a nasopharyngeal cystic disease was hampering the nCPAP treatment of refractory OSAS.https://doi.org/10.4137/CCRep.S24074
collection DOAJ
language English
format Article
sources DOAJ
author Yuma Matsumoto
Hidenori Yokoi
Tetsuya Ikeda
Masachika Fujiwara
Hiroshi Kamma
Naoyuki Kohno
spellingShingle Yuma Matsumoto
Hidenori Yokoi
Tetsuya Ikeda
Masachika Fujiwara
Hiroshi Kamma
Naoyuki Kohno
Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
Clinical Medicine Insights: Case Reports
author_facet Yuma Matsumoto
Hidenori Yokoi
Tetsuya Ikeda
Masachika Fujiwara
Hiroshi Kamma
Naoyuki Kohno
author_sort Yuma Matsumoto
title Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
title_short Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
title_full Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
title_fullStr Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
title_full_unstemmed Intra-Adenoid Cyst: A Case Report with an Immunohistochemical Study and Review of Literature
title_sort intra-adenoid cyst: a case report with an immunohistochemical study and review of literature
publisher SAGE Publishing
series Clinical Medicine Insights: Case Reports
issn 1179-5476
publishDate 2015-01-01
description A woman in her 50s was referred to our department with the chief complaint of nasal congestion and pharyngeal discomfort. The patient had been diagnosed with sleep apnea at the Department of Internal Medicine, and had undergone nasal continuous positive airway pressure (nCPAP) therapy, but her response to the treatment was poor. A cystic lesion occupying the nasopharynx, which was detected by nasopharyngeal fiberscopy, computed tomography, and magnetic resonance imaging, was thought to be the cause of the nasal congestion, pharyngeal discomfort, and obstructive sleep apnea syndrome (OSAS). Consequently, the patient underwent extirpation of the lesion under general anesthesia for the purpose of obtaining a definitive diagnosis as well as for treatment of the nasopharyngeal tumor. The diagnosis of intra-adenoid cyst was eventually made based on the pathological findings, which revealed lymphoid tissue accompanied by expansion of the crypt, as well as inflammatory cell infiltration with follicular hyperplasia. After the operation, the patient reported subjective improvement of her symptoms, and began to respond to the nCPAP therapy for her sleep apnea syndrome. Nasopharyngeal cysts, in particular adult intra-adenoid cyst, are relatively rare. The outcomes of the current case indicated that the presence of a nasopharyngeal cystic disease was hampering the nCPAP treatment of refractory OSAS.
url https://doi.org/10.4137/CCRep.S24074
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