Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunc...

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Main Authors:	Genevieve Walls, Lisa Noonan, Elizabeth Wilson, David Holland, Simon Briggs
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:	http://dx.doi.org/10.1155/2013/508908

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spelling	doaj-ee039b7745c247f0a899174d91acff7e2021-07-02T04:07:55ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-0124210911210.1155/2013/508908Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal OsteomyelitisGenevieve Walls0Lisa Noonan1Elizabeth Wilson2David Holland3Simon Briggs4Department of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Starship Children’s Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Middlemore Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandFungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.http://dx.doi.org/10.1155/2013/508908
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Genevieve Walls Lisa Noonan Elizabeth Wilson David Holland Simon Briggs
spellingShingle	Genevieve Walls Lisa Noonan Elizabeth Wilson David Holland Simon Briggs Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis Canadian Journal of Infectious Diseases and Medical Microbiology
author_facet	Genevieve Walls Lisa Noonan Elizabeth Wilson David Holland Simon Briggs
author_sort	Genevieve Walls
title	Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_short	Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_full	Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_fullStr	Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_full_unstemmed	Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_sort	successful use of locally applied polyhexamethylene biguanide as an adjunct to the treatment of fungal osteomyelitis
publisher	Hindawi Limited
series	Canadian Journal of Infectious Diseases and Medical Microbiology
issn	1712-9532
publishDate	2013-01-01
description	Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.
url	http://dx.doi.org/10.1155/2013/508908
work_keys_str_mv	AT genevievewalls successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis AT lisanoonan successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis AT elizabethwilson successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis AT davidholland successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis AT simonbriggs successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis
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Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

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