Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling

Immune cells infiltrating the tumour microenvironment play critical roles in disease pathogenesis and the immune response. Here the authors present the characterisation of infiltrating B cells in breast tumours by the formation of an atlas created from paired RNA sequence and antigen receptor profil...

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Main Authors:	Qingtao Hu, Yu Hong, Pan Qi, Guangqing Lu, Xueying Mai, Sheng Xu, Xiaoying He, Yu Guo, Linlin Gao, Zhiyi Jing, Jiawen Wang, Tao Cai, Yu Zhang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-22300-2

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spelling	doaj-edfdeb5af37b49f9921c4567b73bb5922021-04-18T11:12:37ZengNature Publishing GroupNature Communications2041-17232021-04-0112111310.1038/s41467-021-22300-2Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profilingQingtao Hu0Yu Hong1Pan Qi2Guangqing Lu3Xueying Mai4Sheng Xu5Xiaoying He6Yu Guo7Linlin Gao8Zhiyi Jing9Jiawen Wang10Tao Cai11Yu Zhang12National Institute of Biological SciencesNational Institute of Biological SciencesXinxiang Central HospitalNational Institute of Biological SciencesNational Institute of Biological SciencesXinxiang Central HospitalXinxiang Central HospitalXinxiang Central HospitalNational Institute of Biological SciencesNational Institute of Biological SciencesNational Institute of Biological SciencesNational Institute of Biological SciencesNational Institute of Biological SciencesImmune cells infiltrating the tumour microenvironment play critical roles in disease pathogenesis and the immune response. Here the authors present the characterisation of infiltrating B cells in breast tumours by the formation of an atlas created from paired RNA sequence and antigen receptor profiling.https://doi.org/10.1038/s41467-021-22300-2
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Qingtao Hu Yu Hong Pan Qi Guangqing Lu Xueying Mai Sheng Xu Xiaoying He Yu Guo Linlin Gao Zhiyi Jing Jiawen Wang Tao Cai Yu Zhang
spellingShingle	Qingtao Hu Yu Hong Pan Qi Guangqing Lu Xueying Mai Sheng Xu Xiaoying He Yu Guo Linlin Gao Zhiyi Jing Jiawen Wang Tao Cai Yu Zhang Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling Nature Communications
author_facet	Qingtao Hu Yu Hong Pan Qi Guangqing Lu Xueying Mai Sheng Xu Xiaoying He Yu Guo Linlin Gao Zhiyi Jing Jiawen Wang Tao Cai Yu Zhang
author_sort	Qingtao Hu
title	Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
title_short	Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
title_full	Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
title_fullStr	Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
title_full_unstemmed	Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
title_sort	atlas of breast cancer infiltrated b-lymphocytes revealed by paired single-cell rna-sequencing and antigen receptor profiling
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-04-01
description	Immune cells infiltrating the tumour microenvironment play critical roles in disease pathogenesis and the immune response. Here the authors present the characterisation of infiltrating B cells in breast tumours by the formation of an atlas created from paired RNA sequence and antigen receptor profiling.
url	https://doi.org/10.1038/s41467-021-22300-2
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Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling

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