Antibiotics Used in Empiric Treatment of Ocular Infections Trigger the Bacterial Rcs Stress Response System Independent of Antibiotic Susceptibility

Antibiotics Used in Empiric Treatment of Ocular Infections Trigger the Bacterial Rcs Stress Response System Independent of Antibiotic Susceptibility

The Rcs phosphorelay is a bacterial stress response system that responds to envelope stresses and in turn controls several virulence-associated pathways, including capsule, flagella, and toxin biosynthesis, of numerous bacterial species. The Rcs system also affects antibiotic tolerance, biofilm form...

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Bibliographic Details
Main Authors: Nathaniel S. Harshaw, Nicholas A. Stella, Kara M. Lehner, Eric G. Romanowski, Regis P. Kowalski, Robert M. Q. Shanks
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antibiotics
Subjects:
Enterobacterales
keratitis
infection
cornea
bacteria
stress response system
Online Access:https://www.mdpi.com/2079-6382/10/9/1033

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