Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms

The dysregulation of intracellular cholesterol homeostasis is associated with several age-related diseases, most notably cardiovascular disease (CVD). Research in this area has benefitted from using computational modelling to study the inherent complexity associated with the regulation of this syste...

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Bibliographic Details
Main Authors: Amy Elizabeth Morgan, Mark Tomás Mc Auley
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/10/314