Differential expression analysis and profiling of hepatic miRNA and isomiRNA in dengue hemorrhagic fever

Abstract Dengue virus causes dengue hemorrhagic fever (DHF) and has been associated to fatal cases worldwide. The liver is one of the most important target tissues in severe cases, due to its intense viral replication and metabolic role. microRNAs role during infection is crucial to understand the r...

Full description

Bibliographic Details
Main Authors: Layanna Freitas de Oliveira, Amanda Araújo Serrão de Andrade, Carla Pagliari, Leda Viegas de Carvalho, Taiana S. Silveira, Jedson Ferreira Cardoso, André Luiz Teles e Silva, Janaina Mota de Vasconcelos, Caroline Aquino Moreira-Nunes, Rommel Mario Rodríguez Burbano, Márcio Roberto Teixeira Nunes, Eduardo José Melo dos Santos, João Lídio da Silva Gonçalves Vianez Júnior
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-72892-w