Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice

The role of scavenger receptor class B, type I (SR-BI) in endothelial cells (EC) was examined in several novel transgenic mouse models expressing SR-BI in endothelium of mice with normal C57Bl6/N, apoE-KO, or Scarb1-KO backgrounds. Mice were also created expressing SR-BI exclusively in endothelium a...

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Main Authors: Boris L. Vaisman, Tatyana G. Vishnyakova, Lita A. Freeman, Marcelo J. Amar, Stephen J. Demosky, Chengyu Liu, John A. Stonik, Maureen L. Sampson, Milton Pryor, Alexander V. Bocharov, Thomas L. Eggerman, Amy P. Patterson, Alan T. Remaley
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/607120