A novel caffeic acid derivative prevents renal remodeling after ischemia/reperfusion injury

A novel caffeic acid derivative prevents renal remodeling after ischemia/reperfusion injury

Acute kidney disease due to renal ischemia/reperfusion (I/R) is a major clinical problem without effective therapies. The injured tubular epithelial cells may undergo epithelial–mesenchymal transition (EMT). It will loss epithelial phenotypes and express the mesenchymal characteristics. The formatio...

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Bibliographic Details
Main Authors: Cheng-Wei Huang, Shih-Yi Lee, Tzu-Tang Wei, Yueh-Hsiung Kuo, Shao-Tung Wu, Hui-Chun Ku
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ischemia/reperfusion
Renal fibrosis
EMT
ECM remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008118

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