The Evaluation of Benefit of Newly Prepared Reversible Inhibitors of Acetylcholinesterase and Commonly Used Pyridostigmine as Pharmacological Pretreatment of Soman-Poisoned Mice

Aim: The ability of four newly prepared reversible inhibitors of acetylcholinesterase (6-chlorotacrine, 7-phenoxytacrine, compounds 1 and 2) and currently used carbamate pyridostigmine to increase the resistance of mice against soman and the efficacy of antidotal treatment of soman-poisoned mice was...

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Bibliographic Details
Main Authors: Jiří Kassa, Jan Korábečný, Eugenie Nepovimová
Format: Article
Language:English
Published: Karolinum Press 2017-06-01
Series:Acta Medica
Subjects:
Online Access:https://actamedica.lfhk.cuni.cz/60/1/0037/