The Gag cleavage product, p12, is a functional constituent of the murine leukemia virus pre-integration complex.

The p12 protein is a cleavage product of the Gag precursor of the murine leukemia virus (MLV). Specific mutations in p12 have been described that affect early stages of infection, rendering the virus replication-defective. Such mutants showed normal generation of genomic DNA but no formation of circ...

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Bibliographic Details
Main Authors: Adi Prizan-Ravid, Efrat Elis, Nihay Laham-Karam, Sara Selig, Marcelo Ehrlich, Eran Bacharach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2978732?pdf=render