Integrin activation through the hematopoietic adapter molecule ADAP regulates dendritic development of hippocampal neurons

Integrin activation through the hematopoietic adapter molecule ADAP regulates dendritic development of hippocampal neurons

Integrin-mediated cell adhesion and signaling is of critical importance for neuronal differentiation. Recent evidence suggests that an inside-out activation of β1-integrin, similar to that observed in hematopoietic cells, contributes to the growth and branching of dendrites. In this study we investi...

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Bibliographic Details
Main Authors: Marlen Thiere, Stefanie Kliche, Bettina Müller, Jan Teuber, Isabell Nold, Oliver Stork
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Adaptor Proteins, Signal Transducing
Hippocampus
Primary Cell Culture
Mouse
integrin
Neurite outgrowth
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00091/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00091/full

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