New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle

Primary abnormalities in the dystrophin gene cause X-linked muscular dystrophy, a highly progressive muscle wasting disorder of childhood. A spontaneous animal model of Duchenne muscular dystrophy is the mdx mouse, which presents a highly interesting phenotype that exhibits considerable variations i...

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Bibliographic Details
Main Authors: Ashling eHolland, Paul eDowling, Kay eOhlendieck
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00109/full